Holby City is a British medical drama television series that airs weekly on BBC One.
The series was created by Tony McHale and Mal Young as a spin-off from the established BBC medical drama Casualty, and premiered on 12 January 1999. It is set in the same hospital as Casualty, Holby General, in the fictional city of Holby, and features occasional crossovers of characters and plots with both Casualty.
The show follows the lives of medical and ancillary staff at the fictional Holby City Hospital. It began with eleven main characters in its first series, all of whom have since left the show. New main characters have been both written in and out of the series since, with a core of fifteen main actors employed on the serial at any given time. In casting the first series, Young sought out actors who were already well-known in the television industry, something which has continued throughout the show's history, with cast members including Patsy Kensit, Jane Asher, Robert Powell and Adrian Edmondson.